Topic 3 · ~12% of Regents exam · Calculation-heavy

Moles & Stoichiometry

The mole is the chemist's counting unit. Every quantitative chemistry question reduces to: convert what you have into moles, use the balanced equation, then convert out of moles to what you want. Get fluent in the three conversions and you've got every calculation on the exam.

1. The mole

A mole is just a counting unit, like a dozen — but much bigger. One mole contains 6.02 × 10²³ particles. This number is called Avogadro's number. We need a unit this large because individual atoms are unimaginably tiny: 12 grams of carbon (about a tablespoon) contains roughly 6 × 10²³ atoms.

1 mole equals
6.02 × 10²³ particles
"Particles" can be
atoms, molecules, ions, formula units
1 mole of gas at STP
22.4 liters

2. Molar mass

The molar mass of any element equals its atomic mass on the Periodic Table, read in grams per mole (g/mol). For a compound, add up the molar masses of each atom in the formula.

Calculating molar mass: H₂O

2 H × 1.01 g/mol = 2.02 g/mol
1 O × 16.00 g/mol = 16.00 g/mol
Total = 18.02 g/mol

So one mole of water weighs about 18 grams.

Calculating molar mass: Ca(NO₃)₂

The subscript 2 applies to everything inside the parentheses.
1 Ca × 40.08 = 40.08
2 N × 14.01 = 28.02
6 O × 16.00 = 96.00  (2 nitrate ions × 3 oxygens each)
Total = 164.10 g/mol

3. The mole map (the most useful diagram on the exam)

Every quantitative chemistry problem boils down to three conversions, all going through moles. Once you know the conversion factors, you can solve any problem on Parts B and C.

Going from…To…Multiply by
GramsMoles1 / molar mass
MolesGramsmolar mass
ParticlesMoles1 / (6.02 × 10²³)
MolesParticles6.02 × 10²³
Liters (gas at STP)Moles1 / 22.4
MolesLiters (gas at STP)22.4

One-step example: grams → moles

How many moles are in 36.04 g of water?

36.04 g × (1 mol / 18.02 g) = 2.00 mol

Two-step example: grams → particles

How many water molecules are in 9.01 g of H₂O?

9.01 g × (1 mol / 18.02 g) × (6.02 × 10²³ molecules / 1 mol)
= 0.500 mol × 6.02 × 10²³ = 3.01 × 10²³ molecules

4. Percent composition by mass

How much of a compound is made of each element, by mass. The formula (also on Reference Table T) is:

% composition = (mass of element in compound / molar mass of compound) × 100

Worked example: % water in CuSO₄·5H₂O

Molar mass of CuSO₄·5H₂O = 63.55 + 32.07 + (4 × 16.00) + 5(18.02) = 249.72 g/mol
Mass of water (5 H₂O) = 5 × 18.02 = 90.10 g/mol

% H₂O = (90.10 / 249.72) × 100 = 36.08%

5. Empirical and molecular formulas

Empirical formula The simplest whole-number ratio of atoms in a compound. Example: glucose (C₆H₁₂O₆) has the empirical formula CH₂O.
Molecular formula The actual number of each atom in one molecule. Glucose's molecular formula is C₆H₁₂O₆. The molecular formula is always a whole-number multiple of the empirical formula.

Going from empirical to molecular

multiplier n = molar mass of molecular formula / molar mass of empirical formula

Example: empirical formula CH₂O has molar mass 30.03 g/mol. If the actual molecule has molar mass 180.18 g/mol, then n = 180.18 / 30.03 = 6. Molecular formula = (CH₂O)₆ = C₆H₁₂O₆.

6. Writing chemical formulas

Ionic compounds (metal + nonmetal)

Charges must cancel. The simplest way: crisscross the absolute value of each charge to become the other ion's subscript, then simplify if possible.

Example: aluminum oxide

Al has charge +3, O has charge −2.
Crisscross: Al gets subscript 2, O gets subscript 3.
Formula: Al₂O₃

Example: calcium nitrate

Ca²⁺ and NO₃⁻ (from Reference Table E).
Crisscross: Ca gets subscript 1 (omitted), NO₃ gets subscript 2 (use parentheses since it's a polyatomic ion).
Formula: Ca(NO₃)₂

Covalent compounds (two nonmetals)

Use Greek prefixes from Reference Table C: mono, di, tri, tetra, penta, hexa, etc. The prefix tells you the subscript directly.

Examples

  • carbon dioxide → CO₂
  • dinitrogen tetraoxide → N₂O₄
  • sulfur hexafluoride → SF₆

Note: the prefix "mono" is dropped from the first element. Carbon dioxide, not "monocarbon dioxide."

7. Balancing chemical equations

The Law of Conservation of Mass (and atoms, and charge) requires that the number of atoms of each element be equal on both sides of the equation. You can change coefficients (the numbers in front), never subscripts inside formulas.

Worked example: combustion of methane

Unbalanced: CH₄ + O₂ → CO₂ + H₂O

  1. Count atoms: Left: 1 C, 4 H, 2 O. Right: 1 C, 2 H, 3 O. Hydrogens and oxygens unbalanced.
  2. Balance H by putting a 2 in front of H₂O: CH₄ + O₂ → CO₂ + 2 H₂O. Now 4 H on each side. Right side has 4 O total.
  3. Balance O by putting a 2 in front of O₂: CH₄ + 2 O₂ → CO₂ + 2 H₂O. 4 O on each side. ✓

Balanced: CH₄ + 2 O₂ → CO₂ + 2 H₂O

8. The five reaction types

The Regents will ask you to identify the type and predict products for each.

TypeGeneral patternExample
Synthesis (combination) A + B → AB 2 Mg + O₂ → 2 MgO
Decomposition AB → A + B 2 H₂O → 2 H₂ + O₂
Single replacement A + BC → AC + B Zn + 2 HCl → ZnCl₂ + H₂
Double replacement AB + CD → AD + CB AgNO₃ + NaCl → AgCl + NaNO₃
Combustion hydrocarbon + O₂ → CO₂ + H₂O C₃H₈ + 5 O₂ → 3 CO₂ + 4 H₂O

Using Table J for single replacement

A single replacement reaction only happens if the element by itself is higher on the activity series (Table J) than the element it's trying to replace.

Example: Zn + 2 HCl → ZnCl₂ + H₂ ✓ (Zn is above H on Table J).
Example: Cu + ZnCl₂ → no reaction (Cu is below Zn on Table J).

9. Stoichiometry: the mole ratio

Once an equation is balanced, the coefficients give you the mole ratio between any two substances in the reaction. This is the heart of every Part C stoichiometry problem.

Worked example: mole-to-mole

Given N₂ + 3 H₂ → 2 NH₃, how many moles of NH₃ form when 6.0 mol of H₂ react completely?

The ratio is 3 mol H₂ : 2 mol NH₃.
6.0 mol H₂ × (2 mol NH₃ / 3 mol H₂) = 4.0 mol NH₃

Worked example: grams-to-grams (full mole map)

Given 2 H₂ + O₂ → 2 H₂O, how many grams of water form from 8.0 g of H₂?

  1. Grams H₂ → moles H₂: 8.0 g × (1 mol / 2.02 g) = 3.96 mol H₂
  2. Moles H₂ → moles H₂O using 2:2 ratio: 3.96 mol H₂O
  3. Moles H₂O → grams H₂O: 3.96 mol × 18.02 g/mol = 71.4 g H₂O

Key terms to know cold

Mole6.02 × 10²³ particles (Avogadro's number)
Molar massMass of one mole of a substance, in g/mol; equals atomic mass for an element
Molar volume of a gas at STP22.4 L/mol
Empirical formulaSimplest whole-number ratio of atoms
Molecular formulaActual number of each atom per molecule
Percent composition% of total mass contributed by each element
CoefficientNumber in front of a formula in a balanced equation
SubscriptSmall number after an element symbol; never changes when balancing
Law of Conservation of MassMass cannot be created or destroyed; both sides of a balanced equation have the same atoms
StoichiometryCalculating amounts of reactants/products using the mole ratio from a balanced equation
SynthesisA + B → AB
DecompositionAB → A + B
Single replacementA + BC → AC + B (check Table J)
Double replacementAB + CD → AD + CB
CombustionHydrocarbon + O₂ → CO₂ + H₂O

Practice questions

Q1 · Multiple Choice

What is the gram-formula mass of Ca(OH)₂?

  1. 57 g/mol
  2. 74 g/mol
  3. 96 g/mol
  4. 112 g/mol
Show answer

(2) 74 g/mol. Ca = 40, O × 2 = 32, H × 2 = 2. Total = 40 + 32 + 2 = 74 g/mol.

Q2 · Multiple Choice

What is the total number of atoms in 0.50 mole of Au?

  1. 3.01 × 10²³
  2. 6.02 × 10²³
  3. 9.85 × 10¹
  4. 1.97 × 10²
Show answer

(1) 3.01 × 10²³. 0.50 mol × 6.02 × 10²³ atoms/mol = 3.01 × 10²³ atoms.

Q3 · Multiple Choice

When the equation _C₂H₆ + _O₂ → _CO₂ + _H₂O is balanced using the smallest whole-number coefficients, the coefficient of O₂ is

  1. 2
  2. 3
  3. 5
  4. 7
Show answer

(4) 7. Balanced: 2 C₂H₆ + 7 O₂ → 4 CO₂ + 6 H₂O. Check: 4 C, 12 H, 14 O on each side. ✓

Q4 · Part B-2 / Short response

Determine the percent composition by mass of nitrogen in the fertilizer NH₄NO₃ (ammonium nitrate).

Show answer

Molar mass of NH₄NO₃: 2(14.01) + 4(1.01) + 3(16.00) = 28.02 + 4.04 + 48.00 = 80.06 g/mol.
Mass of N in formula: 2 × 14.01 = 28.02 g/mol.
% N = (28.02 / 80.06) × 100 = 35.0%

Q5 · Part C / Extended response

Given the balanced equation: 2 Al + 3 Cl₂ → 2 AlCl₃
Calculate the mass of AlCl₃ that can be produced from the complete reaction of 5.40 g of Al. Show your work, including a complete unit-cancellation setup.

Show answer

Step 1: Convert grams Al to moles Al.
5.40 g Al × (1 mol Al / 26.98 g Al) = 0.200 mol Al

Step 2: Use mole ratio (2 Al : 2 AlCl₃, which is 1:1).
0.200 mol Al × (2 mol AlCl₃ / 2 mol Al) = 0.200 mol AlCl₃

Step 3: Convert moles AlCl₃ to grams.
Molar mass of AlCl₃ = 26.98 + 3(35.45) = 133.33 g/mol
0.200 mol × 133.33 g/mol = 26.7 g AlCl₃